Welcome to the Barth Lab!

Research in the Barth lab is focused on understanding how experience assembles and alters the properties of neural circuits in the cerebral cortex, in both normal and disease states.

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  POm thalamocortical input drives layer-specific microcircuits in somatosensory cortex.
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  Unbiased, high-throughput electron microscopy analysis of experience-dependent synaptic changes in the neocortex.
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  Gephyrin-FingR labeling of PV synapses onto cortical pyramidal neurons
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  Experience dependent plasticity in somatosensory cortex.
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  Network assembly and optimization using principles of neural design.
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  alt textExperience dependent plasticity in somatosensory cortex.
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  GFP labelled population of somatostatin containing neocortical interneurons.
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  GABAb receptors silence excitatory synapses in the neocortex.
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  Single-whisker experience enhances response to low-intensity stimuli. © Elena Peterson
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  Quantitative synapse analysis for cell-type specific connectomics.
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  Precisely Timed Nicotinic Activation Drives SST Inhibition in Neocortical Circuits.

Recent Lab News

December 2022  Ajit Ray’s paper is accepted at The Journal of Neuroscience

November 2022  The Sainsbury Wellcome Center talks to Alison Barth https://www.sainsburywellcome.org/web/qa/reflecting-causality-synaptic-changes

November 2022  Ajit Ray’s abstract is selected for a short talk at the annual Barrels meeting in La Jolla

November 2022  Eunsol Park coauthors a News and Views about Npas4 and SST interneurons in Neuron

October 2022  The Barth and Hong labs receive an NIH R21 to study sensory learning and cortical plasticity

October 2022 Eunsol Park presents her work on association learning and inhibitory plasticity at the Air Force Office for Scientific Research conference

Summer 2022 Rachel Swindell receives a NASA fellowship for summer research

June 2022 Eunsol Park’s abstract is selected for a short talk at the Synaptic Transmission GRC in Barga, Italy

May 2022 Fernando Bolio joins the lab as a Research Associate

April 2022 The Barth and Zhao lab receive an RF1 Brain Initiative award to use high-throughput anatomical techniques to study synaptic changes during learning

October 2021 The Barth lab receives an NIH R01 award to study how interneurons generate sparse responses in the cerebral cortex

September 2021 Ajit Ray receives an CMU-IISc joint fellowship

August 2021 Dika Kuljis’s paper on gephyrin-lacking synapses is accepted at IJMS

May 2021 – New Ph.D. students Joseph Christian and Matt Mosso join the Barth Lab

April 2021 – Eunsol Park’s paper is accepted to the International Conference on Learning Representation workshop “AI and the brain”

March 2021 – Undergrad Iulia Loghinov receives NASA suppose for summer research in the Barth Lab

September 2020 – Stories of Women in Neuroscience profile (Link)

September 2020 – Mo Zhu joins the graduate training program at the Center for the Neural Basis of Cognition

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