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Yerneni SS, Werner S, Azambuja JH, Ludwig N, Eutsey R, Aggarwal SD, Lucas PC, Bailey N, Whiteside TL, Campbell PG, Hiller NL. Pneumococcal Extracellular Vesicles Modulate Host Immunity. mBio. 2021 Jul 13:e0165721. doi: 10.1128/mBio.01657-21. Epub ahead of print. PMID: 34253061.
Aggarwal SD, Gullett JM, Fedder T, Safi JPF, Rock CO, Hiller NL. Competence-Associated Peptide BriC Alters Fatty Acid Biosynthesis in Streptococcus pneumoniae. mSphere. 2021 Jun 30;6(3):e0014521. doi: 10.1128/mSphere.00145-21. Epub 2021 May 26. PMID: 34192504.
Aggarwal SD, Lloyd AJ, Yerneni SS, Narciso AR, Shepherd J, Roper DI, Dowson CG, Filipe SR, Hiller NL. A molecular link between cell wall biosynthesis, translation fidelity, and stringent response in Streptococcus pneumoniae. Proc Natl Acad Sci U S A. 2021 Apr 6;118(14):e2018089118.
Aggarwal SD, Yesilkaya H, Dawid SR, Hiller NL. The Pneumococcal Social Network. PLoS Pathogens 16 (10), Oct 2020.
Mueller-Brown K, Le Sage V, French AJ, Jones JE, Padovani GH, Avery AJ, Hiller NL*, Lakdawala SS*. Coinfection of Streptococcus pneumoniae reduces airborne transmission of influenza virus. *co-corresponding authors. bioRxiv 2020.11.10.376442.
Motib Anfal Shakir, Al-Bayati Firas A. Y., Manzoor Irfan, Shafeeq Sulman, Kadam Anagha, Kuipers Oscar P., Hiller N. Luisa, Andrew Peter W., Yesilkaya Hasan. TprA/PhrA Quorum Sensing System Has a Major Effect on Pneumococcal Survival in Respiratory Tract and Blood, and Its Activity Is Controlled by CcpA and GlnR. Front. Cell. Infect. Microbiol., 13 September 2019 | https://doi.org/10.3389/fcimb.2019.00326
Hiller NL, Sá-Leão R. Puzzling Over the Pneumococcal Pangenome. Front Microbiol. 2018 Oct 30;9:2580. doi: 10.3389/fmicb.2018.02580. eCollection 2018. PMID: 30425695
Aggarwal SD, Eutsey R, West-Roberts J, Domenech A, Xu W, Abdullah IT, Mitchell AP, Veening JW, Yesilkaya H, Hiller NL. Function of BriC peptide in the pneumococcal competence and virulence portfolio. PLoS Pathog. 2018 Oct 11;14(10):e1007328. doi: 10.1371/journal.ppat.1007328. eCollection 2018 Oct. PMID: 30308062
Davidson P, Eutsey R, Redler B, Hiller NL, Laub MT, Durand D. Flexibility and constraint: Evolutionary remodeling of the sporulation initiation pathway in Firmicutes. PLoS Genet. 2018 Sep 13;14(9):e1007470. doi: 10.1371/journal.pgen.1007470. eCollection 2018 Sep. PMID: 30212463
Motib A, Guerreiro A, Al-Bayati F, Piletska E, Manzoor I, Shafeeq S, Kadam A, Kuipers O, Hiller L, Cowen T, Piletsky S, Andrew P, Yesilkaya H. Modulation of Quorum Sensing in a Gram Positive Pathogen by Linear Imprinted Copolymers with anti-Infective Properties. Angew Chem Int Ed Engl. 2017 Nov 15. doi: 10.1002/anie.201709313 PMID: 29140595
Antic I, Brothers KM, Stolzer M, Lai H, Powell E, Eutsey R, Cuevas RA, Miao X, Kowalski RP, Shanks RMQ, Durand D, Hiller NL. Gene Acquisition by a Distinct Phyletic Group within Streptococcus pneumoniae Promotes Adhesion to the Ocular Epithelium. mSphere. 2017 Oct 25;2(5). pii: e00213-17. doi: 10.1128/mSphere.00213-17. eCollection 2017 Sep-Oct. PMID: 29085912
Cuevas RA, Eutsey R, Kadam A, West-Roberts JA, Woolford CA, Mitchell AP, Mason KM, Hiller NL. A novel streptococcal cell-cell communication peptide promotes pneumococcal virulence and biofilm formation. Mol Microbiol. 2017 May 29. doi: 10.1111/mmi.13721. PMID: 28557053
Kadam A, Eutsey RA, Rosch J, Miao X, Longwell M, Xu W, Woolford CA, Hillman T, Motib AS, Yesilkaya H, Mitchell AP, Hiller NL. Promiscuous signaling by a regulatory system unique to the pandemic PMEN1 pneumococcal lineage. PLoS Pathog. 2017 May 18;13(5):e1006339. doi: 10.1371/journal.ppat.1006339. eCollection 2017 May. PMID: 28542565
Eutsey RA, Powell E, Dordel J, Salter SJ, Clark TA, Korlach J, Ehrlich GD, Hiller NL. Genetic Stabilization of the Drug-Resistant PMEN1 Pneumococcus Lineage by Its Distinctive DpnIII Restriction-Modification System. mBio. 2015; 6(3):e00173.PubMed [journal] PMID: 26081630, PMCID: PMC4471560
Hiller NL, Ahmed A, Powell E, Martin DP, Eutsey R, Earl J, Janto B, Boissy RJ, Hogg J, Barbadora K, Sampath R, Lonergan S, Post JC, Hu FZ, Ehrlich GD. Generation of genic diversity among Streptococcus pneumoniae strains via horizontal gene transfer during a chronic polyclonal pediatric infection. PLoS pathogens. 2010; 6(9):e1001108. PubMed [journal] PMID: 20862314, PMCID: PMC2940740
Donati C, Hiller NL, Tettelin H, Muzzi A, Croucher NJ, Angiuoli SV, Oggioni M, Dunning Hotopp JC, Hu FZ, Riley DR, Covacci A, Mitchell TJ, Bentley SD, Kilian M, Ehrlich GD, Rappuoli R, Moxon ER, Masignani V. Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species. Genome biology. 2010; 11(10):R107. PubMed [journal] PMID: 21034474, PMCID: PMC3218663
Ehrlich GD, Hiller NL, Hu FZ. What makes pathogens pathogenic. Genome biology. 2008; 9(6):225. PubMed [journal] PMID: 18598378, PMCID: PMC2481411
Hiller NL, Janto B, Hogg JS, Boissy R, Yu S, Powell E, Keefe R, Ehrlich NE, Shen K, Hayes J, Barbadora K, Klimke W, Dernovoy D, Tatusova T, Parkhill J, Bentley SD, Post JC, Ehrlich GD, Hu FZ. Comparative genomic analyses of seventeen Streptococcus pneumoniae strains: insights into the pneumococcal supragenome. Journal of bacteriology. 2007; 189(22):8186-95. PubMed [journal] PMID: 17675389, PMCID: PMC2168654
Bhattacharjee S, Hiller NL, Liolios K, Win J, Kanneganti TD, Young C, Kamoun S, Haldar K. The malarial host-targeting signal is conserved in the Irish potato famine pathogen. PLoS pathogens. 2006; 2(5):e50. PubMed [journal] PMID: 16733545, PMCID: PMC1464399
Hiller NL, Bhattacharjee S, van Ooij C, Liolios K, Harrison T, Lopez-Estraño C, Haldar K. A host-targeting signal in virulence proteins reveals a secretome in malarial infection. Science (New York, N.Y.). 2004; 306(5703):1934-7. PubMed [journal] PMID: 15591203
Hiller NL, Akompong T, Morrow JS, Holder AA, Haldar K. Identification of a stomatin orthologue in vacuoles induced in human erythrocytes by malaria parasites. A role for microbial raft proteins in apicomplexan vacuole biogenesis. The Journal of biological chemistry. 2003; 278(48):48413-21. PubMed [journal]
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